Mastelli is an Italian Pharmaceutical company, founded in 1952.
We develope, manufactures and markets Drug, Class III Medical Devices and cosmetic line to meet patient’s needs.
Mastelli is the worldwide originator company of PDRN since 1952.
In particular in Aesthetic Medicine we mainly produce:
- a huge line of Intradermal skin rejuvenators based on Polynucleotides (class III MD)
- TRIPLEST® line fillers made of natural cross-linked Hyaluronic Acid
- Home Care cosmetic line based on Polynucleotides, Hyaluronic Acid and Vitamin E
Polynucleotides are DNA fragments and they are the main ingredients of our Devices, obtained from fish gonads by means of a particular extraction method.
CLASS III MEDICAL DEVICE
Class III Medical Devices are products that require top quality standards: Mastelli’s Class III Medical Devices are certified by the Italian Health Institute (CE 0373)
INTRADERMAL SKIN REJUVENATORS – POLYNUCLEOTIDES

PLINEST®
Polynucleotides Gel
2 ml pre-filled syringe
Two 30G ½ needles

PLINEST® Body
Polynucleotides Gel
5 x 4 ml vials per box

PLINEST® fast
Polynucleotides Gel
2 ml pre-filled syringe
Two 30G needles

PLINEST® ONE
Polynucleotides Gel
5 x 4 ml vials per box
INTRADERMAL SKIN REJUVENATORS – POLYNUCLEOTIDES & HYALURONIC ACID

NEWEST® One
Polynucleotides and Hyaluronic Acid Gel
5 x 4 ml vials per box

NEWEST®
Polynucleotides and Hyaluronic Acid Gel
2 ml pre-filled syringe
Two 30G ½ needles
SKIN REJUVENATORS – NATURAL FREE HYALURONIC ACID

IALEST®
Hyaluronic Acid gel
2 ml pre-filled syringe
Two 30G needles
TRIPLEST® – FILLERS LINE
An ultrapure monophasic cross-linked hyaluronic acid filler line obtained by means of bio-fermentation thanks to the exclusive Three HA Technology (THT)

TRIPLEST® Classic
1 ml pre-filled syringe – 25 mg/ml
Two 27G needles

TRIPLEST® Lips Smile
1 ml pre-filled syringe – 25 mg/ml
27G and 30G needles

TRIPLEST® Volume
1 ml pre-filled syringe – 25 mg/ml
Two 27G needles
PLINEST CARE – HOME CARE COSMETIC LINE

PLINEST®care is based on natural ingredients:
Nucleotides
Natural Hyaluronic Acid
Vitamin E